Formula 7® Rapid MicroGel® is the only paraben-free Soluble Tolnaftate antifungal microemulsion gel fortified with cosmetic ingredients and bactericidal agents.

Formula 7® Rapid MicroGel® is formulated to address the cause of macerated tissue rapidly and without the stinging effect of alcohol-based gels. Formula 7® Rapid MicroGel® is formulated with both antifungal and bactericidal drugs and fortified with anti-fungal and bactericidal ingredients, penetration enhancers, and cosmetic conditioners and astringents. The Soluble Tolnaftate in Formula 7® Rapid MicroGel® is indicated for 11 organisms. To appreciate the full range of organisms that are sensitive to the formulation please see the question and answer column to the right for your convenience. Our formulation is so unique, there is a patent-pending.

Maceration is defined as the softening and breaking down of skin resulting from prolonged exposure to moisture. It was first described by Jean-Martin Charcot in 1877. Under normal circumstances, epidermal tissue forms an effective barrier against the insult from our external environment. However, when the fungal infection causes the skin to become wet and white (maceration), the skin looses its ability to act as a barrier.

Prolonged exposure of the skin to excessive moisture can result in acute maceration. The outer, flattened layer of epidermal cells becomes rehydrated, causing swelling, and the bonds between the tissue planes weaken. This drastically alters their ability to withstand damage, particularly interdigital friction.

Formula 7® Rapid MicroGel® is formulated to address the cause of the macerated tissue rapidly.  Formula 7® Rapid MicroGel® liquefies at body temperature. Its penetration enhancers draw the tolnaftate into the site of involvement, its cosmetic conditioners and astringents dry the skin and help restore the barrier function of the skin.

What’s the difference between Formula 7® Rapid MicroGel® and Formula 7® Solution?

Formula 7® Rapid MicroGel® is packaged and formulated for the treatment of macerated interdigital tissue, hairy areas of skin, or an infection site that needs a drying agent to help restore the barrier function of the skin.

Formula 7® Solution is packaged and formulated for the treatment of soft tissue around the nail plate. Its intergrated bush makes application over, around, and under the nail an effective way to treat the lateral folds, eponychium, and hyponychium.

When should I use Formula 7® Rapid MicroGel® instead of FungiFoam®?

Use  Formula 7® Rapid MicroGel® on an infection with wet (macerated) skin that needs treatment and drying to restore skin barrier function.  Our MicroGel® is also fortified with bactericidal ingredients.

Use FungiFoam® on an infection with dry cracked skin than needs treatment and a moisturizer to restore skin barrier function.

Is there medical evidence to support Formula 7® Rapid MicroGel® effectiveness?

There are numerous peer-reviewed publications and an FDA monograph that provides clear evidence of the effectiveness of our active ingredient.  We are happy to provide you with the abstracts of the peer-reviewed publications.  Click here for the abstracts of the studies. (here is a link to What Published Studies Tell Us Acetylcysteine Urea Tea Tree Oil).

What organisms are sensitive to the active ingredient in Formula 7® Rapid MicroGel® ?

The active ingredient in Formula 7® Rapid MicroGel® is active against the following organisms:
Microsporum gypseum
M.canis
M. audouinii
M. japonicum
Trichophyton Rubrum
T. mentagrophytes
T. schoenleinni
T. tonsurans
Epidermophyton floccosum
Candida Albacans
Malassezia furfur

What organisms are sensitive to the inactive ingredients in Formula 7® Rapid MicroGel® ?

N-acetyl-l-cysteine (NAC) is a penetration enhancer specifically for tolnaftate flux through nail plate to the site of involvement. Acetylcysteine has antimicrobial properties and breaks down bacterial biofilms of clinically relevant pathogens including:
Pseudomonas aeruginosa
Staphylococcus aureus
methicillin-sensitive and – resistant Staphylococcus aureus (MSSA, MRSA)
vancomycin-resistant Enterococcus faecalis (VRE)
Enterococcus faecalis
Enterobacter cloacae
Staphylococcus epidermidis
Klebsiella pneumoniae
Candida albicans
C. krusei.

Melaleuca Alternifolia (Tea Tree) Oil is a combination of more than 100 components, mostly monoterpenes, sesquiterpenes and terpene alcohols. It adds the benefits of anti-fungal, antiseptic, germicidal and anti-bacterial properties. Clinically relevant susceptible pathogens including:

BACTERIA
Acinetobacter baumannii
Actinomyces viscosus
Actinomyces spp.
Bacillus cereus
Bacteroides spp.
Corynebacterium sp.
Enterococcus faecalis
E. faecium (vancomycin resistant)
Escherichia coli
Fusobacterium nucleatum
Klebsiella pneumoniae
Lactobacillus spp.
Micrococcus luteus
Peptostreptococcus anaerobius
Porphyromonas endodentalis
P. gingivalis
Prevotella spp.
Prevotella intermedia
Propionibacterium acnes
Proteus vulgaris
Pseudomonas aeruginosa
Staphylococcus aureus
S. aureus (methicillin resistant)
S. epidermidis
S. hominis
Streptococcus pyogenes
Veillonella spp.

FUNGI
Alternaria spp.
Aspergillus flavus
A. fumigatus
A. niger
Blastoschizomyces capitatus
Candida albicans
C. glabrata
C. parapsilosis
C. tropicalis
Cladosporium spp.
Cryptococcus neoformans
Epidermophyton flocossum
Fusarium spp.
Malassezia furfur
M. sympodialis
Microsporum canis
M. gypseum
Penicillium spp.
Rhodotorula rubra
Saccharomyces cerevisiae
Trichophyton mentagrophytes
T. rubrum
T. tonsurans
Trichosporon spp.